Description

Methyl 1,3-Dichloroisoquinoline-6-Carboxylate is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactive dichloro and ester functional groups, which allow for selective derivatization to create complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the isoquinoline scaffold for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, luminescent materials, and other advanced functional materials.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and R&D Laboratories: Used in universities and corporate R&D centers for methodological studies and exploring new chemical reactions.

Basic Information

Product Name	Methyl 1,3-Dichloroisoquinoline-6-Carboxylate
CAS No.	1416714-47-0
Molecular Formula	C11H7Cl2NO2
Molecular Weight	256.09 g/mol
Synonyms	1,3-Dichloroisoquinoline-6-carboxylic acid methyl ester; Methyl 1,3-dichloro-6-isoquinolinecarboxylate; 6-Carbomethoxy-1,3-dichloroisoquinoline; 1,3-Dichloro-6-methoxycarbonylisoquinoline; Methyl 1,3-dichloro-6-isoquinolinecarboxylate; 1,3-Dichloro-6-(methoxycarbonyl)isoquinoline; CAS 1416714-47-0
EINECS	Contact for details

Quality Control

Our Methyl 1,3-Dichloroisoquinoline-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.