Description

3-Chloro-6-Nitroisoquinolin-1-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated and nitrated isoquinoline structure. This compound is of significant value in medicinal chemistry for the synthesis of novel drug candidates, particularly those targeting complex biological pathways. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential active pharmaceutical ingredients (APIs) with isoquinoline-based scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Organic Synthesis Reagent: Serves as a versatile precursor for introducing chloro and nitro functional groups into more complex heterocyclic systems.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and herbicides.
• Material Science: Investigated for the creation of specialized organic electronic materials or ligands for catalytic systems.

Basic Information

Product Name	3-Chloro-6-Nitroisoquinolin-1-Ol
CAS No.	1416714-03-8
Molecular Formula	C9H5ClN2O3
Molecular Weight	224.60 g/mol
Synonyms	1-Hydroxy-3-chloro-6-nitroisoquinoline; 3-Chloro-6-nitro-1-isoquinolinol; 3-Chloro-6-nitroisoquinolin-1-ol; 6-Nitro-3-chloro-1-isoquinolinol; 3-Chloro-6-nitro-1-hydroxyisoquinoline; 1-Isoquinolinol, 3-chloro-6-nitro-
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-Nitroisoquinolin-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Standard Grade)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.