Description

6-Bromo-1-Methylisoquinoline is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is crucial for medicinal chemistry research and the synthesis of complex bioactive molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor programs and other small-molecule therapeutics.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Agrochemical Synthesis: Used in the creation of new pesticides and herbicides, leveraging the isoquinoline core for biological activity.
• Material Science Precursor: Acts as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and probes for studying biological mechanisms and target engagement.
• Academic & Industrial R&D: Essential for synthetic organic chemists in universities and corporate R&D labs exploring new chemical reactions and methodologies.

Basic Information

Product Name	6-Bromo-1-Methylisoquinoline
CAS No.	1416712-98-5
Molecular Formula	C₁₀H₈BrN
Molecular Weight	222.08 g/mol
Synonyms	1-Methyl-6-bromoisoquinoline; 6-Bromo-1-methyl-isoquinoline; Isoquinoline, 6-bromo-1-methyl-; 6-Bromo-1-methylisoquinoline; 6-Bromo-1-methyl-isoquinoline; 1416712-98-5; 6-Bromo-1-methyl-isoquinoline (ACI)
EINECS	Contact for details

Quality Control

Our 6-Bromo-1-Methylisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.