Description

Ethyl 2-(5-Bromo-2-(4-(Trifluoromethoxy)Phenyl)Thiazol-4-Yl)Acetate is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters because it integrates a brominated thiazole core with a trifluoromethoxy phenyl group, offering versatile reactivity for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the bioactivity of the thiazole moiety.
• Material Science Research: Serves as a precursor for functionalized organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, halogenated heterocycles.

Basic Information

Product Name	Ethyl 2-(5-Bromo-2-(4-(Trifluoromethoxy)Phenyl)Thiazol-4-Yl)Acetate
CAS No.	1416437-97-2
Molecular Formula	C₁₄H₁₁BrF₃NO₃S
Molecular Weight	410.21 g/mol
Synonyms	Ethyl (5-Bromo-2-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-4-yl)acetate; 2-(5-Bromo-2-(4-(trifluoromethoxy)phenyl)thiazol-4-yl)acetic acid ethyl ester; 1416437-97-2; 5-Bromo-2-(4-trifluoromethoxyphenyl)thiazole-4-acetic acid ethyl ester; Ethyl 5-bromo-2-[4-(trifluoromethoxy)phenyl]-1,3-thiazole-4-acetate; 4-Thiazoleacetic acid, 5-bromo-2-[4-(trifluoromethoxy)phenyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced techniques like HPLC, NMR, and GC-MS to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.