Description

5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Amine Hydrochloride is a high-purity, halogenated heterocyclic building block essential for advanced organic synthesis. This compound is a critical intermediate in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors and other small molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel crop protection agents.
• Material Science: Exploration of its use in the synthesis of organic electronic materials and ligands for catalysis.

Basic Information

Product Name	5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Amine Hydrochloride
CAS No.	1416354-42-1
Molecular Formula	C7H7BrClN3
Molecular Weight	248.51 g/mol
Synonyms	5-Bromo-3-amino-1H-pyrrolo[2,3-b]pyridine hydrochloride; 5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-amine HCl; 3-Amino-5-bromo-1H-pyrrolo[2,3-b]pyridine hydrochloride; 5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-amine monohydrochloride; 5-Bromo-7-azaindol-3-amine hydrochloride; 5-Bromo-3-aminopyrrolo[2,3-b]pyridine hydrochloride; 1416354-42-1
EINECS	Contact for details

Quality Control

Our 5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.