Description

2-Iodo-6,7-Dihydroindolizin-8(5H)-One is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex pharmaceutical molecules and functional materials, enabling critical carbon-iodine bond transformations. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel indolizine-based scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly for targeted therapies.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products.
• Material Science: Acts as a building block for creating specialized organic electronic materials and ligands for catalysis.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings.
• Medicinal Chemistry Library Synthesis: Employed in the parallel and combinatorial synthesis of diverse compound libraries for high-throughput screening.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.

Basic Information

Product Name	2-Iodo-6,7-Dihydroindolizin-8(5H)-One
CAS No.	1416221-39-0
Molecular Formula	C8H8INO
Molecular Weight	261.06 g/mol
Synonyms	2-Iodo-5,6,7,8-tetrahydroindolizin-8-one; 8(5H)-Indolizinone, 2-iodo-6,7-dihydro-; 2-Iodo-6,7-dihydro-8(5H)-indolizinone; 2-Iododihydroindolizinone; 2-Iodo-5,6,7,8-tetrahydroindolizin-8-one; 1416221-39-0; AI3-35336
EINECS	Contact for details

Quality Control

Our 2-Iodo-6,7-Dihydroindolizin-8(5H)-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.