Description

3-(Difluoromethyl)-1H-Indazole is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its unique indazole core modified with a difluoromethyl group makes it a critical intermediate for developing novel pharmaceuticals and agrochemicals. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the difluoromethyl group can improve metabolic stability and bioavailability.
• Chemical Biology Probe Development: Serves as a versatile scaffold for designing molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a building block for advanced organic materials, such as ligands for catalysts or components in specialty polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	3-(Difluoromethyl)-1H-Indazole
CAS No.	1415739-85-3
Molecular Formula	C8H6F2N2
Molecular Weight	168.14 g/mol
Synonyms	1H-Indazole, 3-(difluoromethyl)-; 3-(Difluoromethyl)-1H-indazole; 3-Difluoromethyl-1H-indazole; 3-Difluoromethylindazole; 1415739-85-3
EINECS	Contact for details

Quality Control

Every batch of 3-(Difluoromethyl)-1H-Indazole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.