Description

4-Bromo-2-(naphthalen-1-yl)thiazole is a structurally distinctive heterocyclic aromatic compound featuring a thiazole core substituted with a bromine atom at the 4-position and a naphthyl group at the 2-position. This molecular architecture confers high electron affinity, thermal stability, and tunable optoelectronic properties—making it a valuable building block for advanced functional materials. It is primarily utilized by R&D laboratories and fine chemical manufacturers in the development of organic semiconductors, pharmaceutical intermediates, and luminescent sensors. The compound is referenced globally as 4-Bromo-2-(Naphthalen-1-Yl)Thiazole CAS NO 1415562-89-8 to ensure unambiguous identification across supply chains and regulatory documentation.

Application

• Key intermediate in the synthesis of OLED emitters and host materials for blue/green electroluminescent devices
• Building block for kinase inhibitors and antiproliferative agents in medicinal chemistry campaigns
• Structural motif in metal-organic frameworks (MOFs) and luminescent coordination polymers
• Photoactive component in organic photovoltaic (OPV) donor-acceptor systems
• Reagent for Suzuki-Miyaura and Stille cross-coupling reactions to access extended π-conjugated architectures
• Fluorescent probe scaffold for bioimaging due to naphthalene-enhanced quantum yield and red-shifted emission
• Monomer in the preparation of thiazole-based conductive polymers and electrochromic materials
• Chiral ligand precursor via asymmetric functionalization of the bromo site for transition-metal catalysis

Basic Information

Product Name	4-Bromo-2-(naphthalen-1-yl)thiazole
CAS No.	1415562-89-8
Molecular Formula	C13H8BrNS
Molecular Weight	306.18 g/mol
Synonyms	4-Bromo-2-(1-naphthyl)thiazole; 4-Bromo-2-(naphthalen-1-yl)-1,3-thiazole; 1,3-Thiazole, 4-bromo-2-(1-naphthalenyl)-; NSC 100714; AKOS B001051; Z1922372028; STK025478; BRD-K22543492
EINECS	Not listed (not yet assigned)

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is verified for identity, purity, and structural integrity using orthogonal analytical methods including HPLC, NMR, IR spectroscopy, and elemental analysis. Certificates of Analysis (COA) are available upon request and include assay, residual solvents, heavy metals, and related substances data. All manufacturing adheres to ISO 9001-certified quality management systems and supports REACH compliance for global distribution.

Storage

Preserve in a tightly closed container, protected from light. Store at room temperature (15–25°C) in a dry, well-ventilated area. Avoid exposure to moisture, strong oxidizing agents, and strong alkalis. Handle under inert atmosphere if prolonged storage is required.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Assay (HPLC)	≥ 98.5%
Melting Point	142–146°C
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to reference 1H and 13C NMR data
Residual Solvents (GC)	Meets ICH Q3C Class 3 limits
Heavy Metals (as Pb)	≤ 10 ppm
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.