Description

2-(4-Bromothiazol-2-Yl)-N,N-dimethylaniline is a high-purity heterocyclic aromatic amine featuring a brominated thiazole core coupled with a tertiary dimethylamino substituent. This structural motif confers exceptional utility as a key building block in the synthesis of advanced functional materials and pharmaceutical intermediates. It is critically employed by R&D laboratories and fine chemical manufacturers developing next-generation optoelectronic compounds, kinase inhibitors, and photoactive dyes. The compound is widely sought after for its reliable reactivity in palladium-catalyzed cross-coupling reactions and its role in constructing conjugated π-systems.

Application

• Synthesis of organic light-emitting diode (OLED) emitters and host materials
• Key intermediate in the production of selective protein kinase inhibitors (e.g., BTK, EGFR inhibitors)
• Building block for fluorescent probes and bioimaging agents targeting cellular thiols or pH gradients
• Monomer in the development of thiazole-based conductive polymers and electrochromic materials
• Chemical scaffold for structure–activity relationship (SAR) studies in antitumor and antimicrobial drug discovery
• Reagent in Suzuki–Miyaura and Buchwald–Hartwig amination reactions for C–C and C–N bond formation
• Component in photoinitiator systems for UV-curable coatings and inks
• Intermediate for high-performance liquid crystal (LC) dopants with enhanced dielectric anisotropy

Basic Information

Product Name	2-(4-Bromothiazol-2-Yl)-N,N-dimethylaniline
CAS No.	1415562-86-5
Molecular Formula	C11H11BrN2S
Molecular Weight	299.19 g/mol
Synonyms	2-(4-Bromo-1,3-thiazol-2-yl)-N,N-dimethylaniline; N,N-Dimethyl-2-(4-bromothiazol-2-yl)aniline; 2-(4-Bromothiazol-2-yl)-N,N-dimethylbenzenamine; 4-Bromo-2-(N,N-dimethyl-p-phenylenediamine)thiazole; DBDTA; 2-(4-Bromo-1,3-thiazol-2-yl)-N,N-dimethylbenzenamine; CAS 1415562-86-5; NSC 758121
EINECS	Not listed

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches are verified for identity (IR, HPLC, NMR), purity (≥99.0% by HPLC), residual solvents (ICH Q3C compliant), heavy metals (≤10 ppm), and halide content. Testing adheres to ACS Reagent Grade and EP/USP general chapters where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at room temperature (15–25°C) in a dry, well-ventilated area. Strictly light-sensitive (protect from all light exposure). Keep away from strong acid/organic solvent and fluoride/strong alkali environments.

Specification

Item	Specification
Appearance	Pale yellow to off-white crystalline powder
Identity (IR)	Conforms to reference standard
Identity (HPLC)	Retention time matches reference
Assay (by HPLC)	≥99.0%
Related Substances (by HPLC)	≤0.5% total impurities
Residue on Ignition	≤0.1%
Water (Karl Fischer)	≤0.2%
Melting Point	118–122°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.