Description

3-(6-Benzyloxy-1H-Indol-3-Yl)-3-Oxo-Propionitrile is a high-purity, synthetically versatile indole derivative. This compound serves as a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis: Serves as a versatile precursor for constructing more complex heterocyclic frameworks and functionalized indole structures.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies due to its specific molecular scaffold.
• Process Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-(6-Benzyloxy-1H-Indol-3-Yl)-3-Oxo-Propionitrile
CAS No.	1415393-24-6
Molecular Formula	C18H14N2O2
Molecular Weight	290.32 g/mol
Synonyms	3-(6-Benzyloxy-1H-indol-3-yl)-3-oxopropanenitrile; 3-Oxo-3-(6-phenylmethoxy-1H-indol-3-yl)propanenitrile; 6-Benzyloxy-3-(2-cyanoacetyl)indole; 3-(2-Cyanoacetyl)-6-benzyloxyindole; 6-Benzyloxyindole-3-acetonitrile ketone; 3-(6-Benzyloxyindol-3-yl)-3-oxopropionitrile; BNOP
EINECS	Contact for details

Quality Control

Our production of 3-(6-Benzyloxy-1H-Indol-3-Yl)-3-Oxo-Propionitrile adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for research and development purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be stored away from light. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.