Description

7-Bromo-5-Fluoro-2-Methyl-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic molecules.
• API Synthesis: Serves as a critical precursor in the multi-step manufacturing process of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Tool Compound: Utilized in preclinical research to investigate biological pathways and receptor interactions.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects in CDMOs (Contract Development and Manufacturing Organizations).

Basic Information

Product Name	7-Bromo-5-Fluoro-2-Methyl-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride
CAS No.	1414958-49-8
Molecular Formula	C₁₀H₁₀BrClFN
Molecular Weight	278.55 g/mol
Synonyms	7-Bromo-5-fluoro-2-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-7-bromo-5-fluoro-2-methylisoquinoline hydrochloride; 7-Bromo-5-fluoro-2-methyl-3,4-dihydro-1H-isoquinoline hydrochloride; 1414958-49-8; 7-Br-5-F-2-Me-THIQ·HCl
EINECS	Contact for details

Quality Control

Our 7-Bromo-5-Fluoro-2-Methyl-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.