Description

3-(3-Methyl-1H-Indol-2-Yl)-3-Oxopropanenitrile is a specialized indole-based nitrile building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex heterocyclic molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists working in medicinal chemistry, agrochemical discovery, and the synthesis of novel functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core structure.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a building block for electron-transport or host materials in the creation of advanced display technologies.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for transition metal-catalyzed reactions, enabling novel synthetic pathways.
• Fluorescent Probe Development: Utilized as a core structure in the design of sensitive molecular probes for biochemical and diagnostic applications.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry and the exploration of new indole derivative reactivity.

Basic Information

Product Name	3-(3-Methyl-1H-Indol-2-Yl)-3-Oxopropanenitrile
CAS No.	1414944-13-0
Molecular Formula	C₁₂H₁₀N₂O
Molecular Weight	198.22 g/mol
Synonyms	3-(3-Methyl-1H-indol-2-yl)-3-oxopropanenitrile; 2-Acetyl-3-methylindole-2-carbonitrile; 3-Oxo-3-(3-methyl-1H-indol-2-yl)propanenitrile; 3-Methyl-2-cyanomethylindole; 2-(Cyanomethyl)-3-methyl-1H-indole; 3-Methylindole-2-acetonitrile; 3-Methyl-1H-indole-2-acetonitrile; 2-(2-Cyanoacetyl)-3-methylindole
EINECS	Contact for details

Quality Control

Our 3-(3-Methyl-1H-Indol-2-Yl)-3-Oxopropanenitrile is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including HPLC, GC-MS, and NMR for comprehensive characterization. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.