Description

5-Iodo-2-Methylthiazole is a high-purity, halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its reactivity, particularly in cross-coupling reactions, enabling the construction of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides, leveraging the thiazole core's bioactivity.
• Material Science: Serves as a precursor for functionalized ligands, organic semiconductors, and other specialty chemicals.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings to introduce the 2-methylthiazole moiety.
• Chemical Biology: Utilized as a probe or tag in bioconjugation chemistry due to the reactive iodine handle.
• Academic & Industrial R&D: Fundamental building block for method development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	5-Iodo-2-Methylthiazole
CAS No.	1412902-50-1
Molecular Formula	C4H4INS
Molecular Weight	225.05 g/mol
Synonyms	2-Methyl-5-iodothiazole; 5-Iodo-2-methyl-1,3-thiazole; 5-Iodo-2-methyl-thiazole; Thiazole, 5-iodo-2-methyl-; Iodomethylthiazole
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-Methylthiazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable material for critical synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.