Description

2-Bromo-6-(Thiazol-5-Yl)Pyridine is a high-value heterocyclic building block featuring a bromopyridine core linked to a thiazole moiety. This compound matters as a versatile and critical intermediate in modern pharmaceutical and agrochemical research, enabling the synthesis of complex molecules through cross-coupling and other metal-catalyzed reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require complex heterocyclic scaffolds.
• Material Science: Serves as a building block for creating organic ligands in catalysis and for synthesizing advanced organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form biaryl and C-N bonds.
• Chemical Biology & Proteomics: Utilized in the design of molecular probes and tags for studying biological systems and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Bromo-6-(Thiazol-5-Yl)Pyridine
CAS No.	1411985-18-6
Molecular Formula	C8H5BrN2S
Molecular Weight	241.11 g/mol
Synonyms	5-(6-Bromopyridin-2-yl)thiazole; 6-Bromo-2-(thiazol-5-yl)pyridine; 2-(Thiazol-5-yl)-6-bromopyridine; 2-Bromo-6-(1,3-thiazol-5-yl)pyridine; 1411985-18-6; 5-(6-Bromo-2-pyridinyl)-1,3-thiazole; Thiazole, 5-(6-bromo-2-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(Thiazol-5-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.