Description

7-Fluoro-5-Methoxyisoquinolin-1(2H)-One is a high-value, fluorinated isoquinolinone derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both fluorine and methoxy substituents, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical discovery, and materials science. Its precise synthesis and high purity are paramount for ensuring the success and reproducibility of downstream research and development processes.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, neurology, and anti-infective therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and pesticides, leveraging the bioactivity-enhancing properties of the fluorine atom.
• Material Science Precursor: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated system and substituent effects.
• Chemical Biology Probe Development: Serves as a core scaffold for creating fluorescent tags or molecular probes to study biological processes.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including novel fluorination and heterocycle formation reactions.

Basic Information

Product Name	7-Fluoro-5-Methoxyisoquinolin-1(2H)-One
CAS No.	1409950-66-8
Molecular Formula	C₁₀H₈FNO₂
Molecular Weight	193.17 g/mol
Synonyms	1(2H)-Isoquinolinone, 7-fluoro-5-methoxy-; 7-Fluoro-5-methoxy-1,2-dihydroisoquinolin-1-one; 7-Fluoro-5-methoxy-1H-isoquinolin-1-one; 5-Methoxy-7-fluoroisoquinolin-1(2H)-one; 7-Fluoro-5-methoxyisoquinolin-1-ol (tautomer); FMOIQ; 7-F-5-MeO-IQ-1-one
EINECS	Contact for details

Quality Control

Our 7-Fluoro-5-Methoxyisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF for moisture content, to ensure it meets the stringent requirements for research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.