Description

8-Azabicyclo[3.2.1]Octan-2-Ol is a specialized bicyclic organic compound featuring a nitrogen bridgehead, which serves as a crucial advanced pharmaceutical intermediate. Its unique bridged structure makes it a valuable scaffold for medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. This high-purity building block is essential for research and development in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug discovery.
• Medicinal Chemistry Research: Used as a core scaffold to develop new chemical entities (NCEs) and probe structure-activity relationships (SAR) due to its constrained three-dimensional geometry.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides with novel modes of action.
• Catalyst and Ligand Development: The nitrogen-containing bicyclic structure can be utilized to develop novel chiral ligands for asymmetric synthesis.
• Academic and R&D Laboratories: Employed in organic synthesis research for constructing complex natural product analogs and heterocyclic compounds.

Basic Information

Product Name	8-Azabicyclo[3.2.1]Octan-2-Ol
CAS No.	1408075-80-8
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	8-Azabicyclo[3.2.1]octan-2-ol; 2-Hydroxy-8-azabicyclo[3.2.1]octane; Nortropan-2-ol; 8-Azanorbornan-2-ol; 2-Nortropanol; 8-Azabicyclo[3.2.1]octan-2-ol (major); Tropane-2-ol derivative
EINECS	Contact for details

Quality Control

Our 8-Azabicyclo[3.2.1]Octan-2-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for advanced synthetic applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC purity data, chiral purity, and identification spectra (IR, NMR, MS). Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.