Description

7-Amino-5,8-Dichloro-1,2,3,4-Tetrahydroisoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique tetrahydroisoquinoline scaffold. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly for central nervous system (CNS) and oncological targets.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic compounds due to its reactive amino and chloro functional groups.
• Agrochemical Research: Potential application in the development of new active ingredients for crop protection.
• Biochemical Tool Compound: Serves as a research chemical for studying biological pathways and enzyme interactions.

Basic Information

Product Name	7-Amino-5,8-Dichloro-1,2,3,4-Tetrahydroisoquinoline
CAS No.	1408075-55-7
Molecular Formula	C9H10Cl2N2
Molecular Weight	217.10 g/mol
Synonyms	5,8-Dichloro-1,2,3,4-tetrahydro-7-isoquinolinamine; 7-Amino-5,8-dichloro-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-5,8-dichloro-7-isoquinolinamine; 5,8-Dichloro-7-amino-1,2,3,4-tetrahydroisoquinoline; 7-Amino-5,8-dichlorotetrahydroisoquinoline; 1408075-55-7; 5,8-Dichloro-1,2,3,4-tetrahydroisoquinolin-7-amine
EINECS	Contact for details

Quality Control

Our 7-Amino-5,8-Dichloro-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.