Description

Exo-8-Azabicyclo[3.2.1]Octan-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a rigid, bridged bicyclic structure. This compound is valued for its role as a key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and antiviral therapeutics. It is primarily sought by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in innovative drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel APIs, especially in CNS-targeting drugs.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a starting material or key intermediate in scaling up synthetic routes under GMP conditions.
• Asymmetric Synthesis: Utilized as a scaffold to introduce stereochemical complexity in target molecules.
• Protease Inhibitor Development: Potential building block for compounds targeting viral proteases.
• Ligand and Catalyst Synthesis: Precursor for creating novel chiral ligands or organocatalysts.

Basic Information

Product Name	Exo-8-Azabicyclo[3.2.1]Octan-2-Carboxylic Acid
CAS No.	1408075-36-4
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	8-Azabicyclo[3.2.1]octane-2-carboxylic acid, exo-; (1R,2S,5S)-8-Azabicyclo[3.2.1]octane-2-carboxylic acid; Tropane-2-carboxylic acid, 8-aza-; exo-8-Azanorbornane-2-carboxylic acid; 2-Carboxy-8-azabicyclo[3.2.1]octane; 1408075-36-4; 8-Azanorbornane-2-carboxylic acid, exo-
EINECS	Contact for details

Quality Control

Our Exo-8-Azabicyclo[3.2.1]Octan-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (exo-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.