Description

4-Aminobicyclo[2.2.2]octan-1-ol hydrochloride is a high-purity, functionalized bicyclic amine hydrochloride salt of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block, offering a rigid, three-dimensional scaffold that is crucial for modulating the physicochemical properties and biological activity of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral targets.
• Asymmetric Catalyst Ligand: The rigid bicyclo[2.2.2]octane structure and amine functionality make it a candidate for developing novel ligands in asymmetric catalysis.
• Agrochemical Research: Used in the research and development of new herbicides, fungicides, and insecticides that require complex, sterically defined amine components.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with unique thermal or mechanical properties.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, exploring new ring systems and reaction pathways.

Basic Information

Product Name	4-Aminobicyclo[2.2.2]octan-1-ol hydrochloride
CAS No.	1403864-74-3
Molecular Formula	C8H16ClNO
Molecular Weight	177.67 g/mol
Synonyms	1-Amino-4-hydroxybicyclo[2.2.2]octane hydrochloride; 4-Amino-1-hydroxybicyclo[2.2.2]octane HCl; Bicyclo[2.2.2]octan-1-ol, 4-amino-, hydrochloride; 4-Aminobicyclo[2.2.2]octan-1-ol HCl; 1-Hydroxy-4-aminobicyclo[2.2.2]octane hydrochloride; 4-ABO-HCl; 1-Amino-4-hydroxyadamantane analogue hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Aminobicyclo[2.2.2]octan-1-ol hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.