Description

6-Bromo-2,3-Dihydro-3,3-Dimethyl-1H-Isoindol-1-One is a high-purity brominated isoindolinone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile halogenated scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of new crop protection agents and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probe Development: Utilized as a core structure for creating molecular probes and tool compounds to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies in cross-coupling reactions, heterocyclic chemistry, and scaffold diversification.

Basic Information

Item	Details
Product Name	6-Bromo-2,3-Dihydro-3,3-Dimethyl-1H-Isoindol-1-One
CAS No.	1403766-79-9
Molecular Formula	C10H10BrNO
Molecular Weight	240.10 g/mol
Synonyms	6-Bromo-3,3-dimethylisoindolin-1-one; 6-Bromo-3,3-dimethyl-2,3-dihydro-1H-isoindol-1-one; 6-Bromo-3,3-dimethyl-1-isoindolinone; 1H-Isoindol-1-one, 6-bromo-2,3-dihydro-3,3-dimethyl-; 1403766-79-9; 6-Bromo-3,3-dimethylisoindolinone
EINECS	Contact for details

Quality Control

Our 6-Bromo-2,3-Dihydro-3,3-Dimethyl-1H-Isoindol-1-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.