Description

Ethyl 2-Boc-6-Oxo-Octahydro-Isoquinoline-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a protected, reactive scaffold for constructing novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and API manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules, particularly in medicinal chemistry research.
• API Synthesis: Used in the development and production of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical studies.
• Peptidomimetic Research: Serves as a constrained scaffold in the design of peptide-like compounds to improve metabolic stability and bioavailability.
• Alkaloid Analog Synthesis: Facilitates the construction of tetrahydroisoquinoline-based analogs for biological screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Employed in route scouting and optimization for scalable, cost-effective manufacturing processes.
• Academic & Industrial R&D: A valuable reagent for universities and biotech companies exploring new chemical entities in therapeutic areas such as oncology and neurology.

Basic Information

Product Name	Ethyl 2-Boc-6-Oxo-Octahydro-Isoquinoline-3-Carboxylate
CAS No.	1403766-62-0
Molecular Formula	C₁₇H₂₇NO₅
Molecular Weight	325.40 g/mol
Synonyms	Ethyl 2-[(tert-Butoxycarbonyl)amino]-6-oxo-1,2,3,4,6,7,8,8a-octahydroisoquinoline-3-carboxylate; 2-Boc-6-Oxo-Octahydro-Isoquinoline-3-Carboxylic Acid Ethyl Ester; 1,2,3,4,6,7,8,8a-Octahydro-2-[[(1,1-dimethylethoxy)carbonyl]amino]-6-oxo-3-isoquinolinecarboxylic Acid Ethyl Ester; 3-Carbethoxy-2-(N-Boc-amino)-6-oxo-octahydroisoquinoline; BOC-Protected Octahydroisoquinoline Derivative; Ethyl 2-(tert-Butoxycarbonylamino)-6-oxodecahydroisoquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Boc-6-Oxo-Octahydro-Isoquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.