Description

4-Oxo-Octahydro-Isoindole-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its bicyclic, fused-ring structure containing both carboxylic acid and lactam functionalities. This compound matters as a critical building block in the synthesis of complex, biologically active molecules, enabling the development of novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for projects targeting central nervous system (CNS) disorders, pain management, and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for neurological targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in drug discovery programs.
• Protease Inhibitor Synthesis: Serves as a core structure in the development of inhibitors for various protease enzymes.
• Peptidomimetic Development: Its constrained, bicyclic framework is valuable for creating stable peptide mimics with enhanced bioavailability.
• Chemical Biology Probes: Utilized in the design of molecular probes to study enzyme function and biological pathways.
• Process Chemistry & Scale-up: Serves as a critical intermediate in the optimization and commercial-scale manufacturing of candidate drugs.

Basic Information

Item	Details
Product Name	4-Oxo-Octahydro-Isoindole-1-Carboxylic Acid
CAS No.	1403766-61-9
Molecular Formula	C9H13NO3
Molecular Weight	183.20 g/mol
Synonyms	Octahydro-4-oxo-1H-isoindole-1-carboxylic acid; 1-Carboxy-4-oxooctahydroisoindole; 4-Oxo-octahydroisoindole-1-carboxylic acid; (1S,3aR,7aS)-4-Oxo-octahydro-1H-isoindole-1-carboxylic acid (stereoisomer); Isoindole-1-carboxylic acid, octahydro-4-oxo-; Advanced Pharmaceutical Intermediate 1403766-61-9; Bicyclic Lactam Carboxylic Acid
EINECS	Contact for details

Quality Control

Our 4-Oxo-Octahydro-Isoindole-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance data for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.