Description

Sarolaner is a potent and selective isoxazoline-class ectoparasiticide, widely recognized for its efficacy against fleas and ticks. Its primary value lies in its novel mode of action, targeting invertebrate-specific GABA-gated chloride channels to provide rapid and long-lasting control. This high-purity active pharmaceutical ingredient (API) is essential for manufacturers developing next-generation veterinary pharmaceutical formulations, particularly in the companion animal health sector.

Application

• Veterinary Pharmaceutical API: Primary active ingredient in topical spot-on solutions and oral chews for dogs and cats.
• Ectoparasite Control Formulations: Used in products targeting fleas (Ctenocephalides felis), ticks (Ixodes scapularis, Rhipicephalus sanguineus), and mites.
• Companion Animal Health Products: Key component in prescription and over-the-counter (OTC) parasiticides for pet care.
• Agricultural & Livestock Parasiticides: Potential use in R&D for formulations targeting external parasites in livestock, subject to regional regulatory approvals.
• Research & Development: Reference standard and building block for synthesizing novel isoxazoline derivatives in agrochemical and pharmaceutical research.

Basic Information

Product Name	Sarolaner
CAS No.	1398609-39-6
Molecular Formula	C24H16Cl2F3N3O3
Molecular Weight	506.30 g/mol
Synonyms	Sarolaner; 1-(5'-Sulfamoyl-4-biphenylyl)-3-(trifluoromethyl)-5-(2,6-dichloro-4-trifluoromethylphenoxy)-1H-pyrazole; Simparica (Brand Name); A1443; Isoxazoline Parasiticide; 4-[5-(3,5-Dichloro-4-{[1,1,1-trifluoro-2-(trifluoromethyl)propan-2-yl]oxy}phenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-methyl-2-(methyloxy)benzamide
EINECS	Contact for details

Quality Control

Our Sarolaner is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) that details purity, identity, and impurity profiles. Quality assurance protocols are designed to meet the stringent requirements for Active Pharmaceutical Ingredient (API) production, supporting compliance with cGMP and relevant veterinary pharmacopoeia standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.