Description

Ethyl 2-Bromopropionate-3,3,3-D3 is a deuterium-labeled isotopologue of ethyl 2-bromopropionate, a valuable building block in synthetic organic chemistry. This compound is specifically designed for use in advanced research and development, particularly in the fields of pharmaceutical chemistry and material science, where isotopic labeling is essential for mechanistic studies, metabolic pathway tracing, and analytical method development. It serves as a critical reagent for chemists and researchers in pharmaceutical, agrochemical, and academic institutions requiring high-purity, isotopically enriched intermediates.

Application

• Pharmaceutical Research & Development: As a deuterated synthon for the preparation of isotopically labeled active pharmaceutical ingredients (APIs) and metabolites for pharmacokinetic (PK) and pharmacodynamic (PD) studies.
• Analytical Chemistry Standards: Used as an internal standard in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy to ensure accurate measurement and analysis.
• Mechanistic Studies: Employed in reaction mechanism elucidation and isotope effect investigations due to the kinetic isotope effect (KIE) imparted by the deuterium atoms.
• Agrochemical Development: A key intermediate in the synthesis of novel, labeled agrochemical compounds for environmental fate and metabolism studies.
• Material Science: Potential use in the synthesis of specialty polymers and advanced materials where deuterium incorporation modifies physical properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development of labeled compounds.

Basic Information

Item	Detail
Product Name	Ethyl 2-Bromopropionate-3,3,3-D3
CAS No.	1398066-14-2
Molecular Formula	C5H6D3BrO2
Molecular Weight	181.03 g/mol (approx.)
Synonyms	Ethyl 2-Bromopropionate-d3; Ethyl α-Bromopropionate-d3; 2-Bromopropionic Acid Ethyl Ester-d3; Propanoic acid, 2-bromo-, ethyl ester-3,3,3-d3; Ethyl 2-bromopropanoate-d3; Deuterated Ethyl 2-Bromopropionate; [3,3,3-2H3]Ethyl 2-bromopropionate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromopropionate-3,3,3-D3 is manufactured under strict quality control protocols to ensure high chemical purity and isotopic enrichment. Each batch is characterized by advanced analytical techniques including NMR, GC-MS, and HPLC to confirm identity, chemical purity, and deuterium incorporation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Isotopic Purity (Deuterium Content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.