Description

n-Acetylpiperazine-D4 is a deuterium-labeled analog of n-acetylpiperazine, a versatile chemical building block. This isotopically labeled compound is essential for advanced research and development, particularly in the fields of analytical chemistry and life sciences. It is primarily used by pharmaceutical researchers, contract research organizations (CROs), and chemical manufacturers involved in the synthesis of deuterated compounds for use as internal standards, metabolic tracers, and in drug discovery programs.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis for accurate measurement of its non-deuterated counterpart or related metabolites.
• Metabolic Pathway Tracing: Employed in pharmacokinetic (PK) and drug metabolism studies to track the absorption, distribution, metabolism, and excretion (ADME) of pharmaceutical compounds.
• Deuterated Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex deuterium-labeled active pharmaceutical ingredients (APIs) for improved metabolic stability.
• NMR Spectroscopy: Utilized as a probe in nuclear magnetic resonance (NMR) studies due to the distinct magnetic properties of deuterium atoms.
• Chemical Research & Development: Acts as a stable, isotopically labeled reagent in mechanistic studies and in the development of novel synthetic methodologies.

Basic Information

Product Name	n-Acetylpiperazine-D4
CAS No.	1398065-90-1
Molecular Formula	C6H8D4N2O
Molecular Weight	128.18 g/mol
Synonyms	1-Acetylpiperazine-2,2,3,3,5,5,6,6-d8; N-Acetylpiperazine-d4; Perdeuterated N-Acetylpiperazine; 1-Acetylpiperazine-d4; Deuterated N-Acetylpiperazine; Acetylpiperazine-d4; 1-Piperazineacetamide-d4; 2,2,3,3,5,5,6,6-Octadeutero-1-acetylpiperazine
EINECS	Contact for details

Quality Control

Our n-Acetylpiperazine-D4 is manufactured under strict quality control protocols to ensure high isotopic purity and chemical integrity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D-content), chemical purity, and identity confirmation. We adhere to relevant industry standards for fine chemicals and can provide material suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.