Description

p-(Dimethyl-D6-Amino)Nitrosobenzene is a deuterium-labeled aromatic nitroso compound, serving as a critical stable isotope-labeled intermediate for advanced research and development. Its core value lies in providing a non-radioactive isotopic tracer for mechanistic studies, metabolic pathway analysis, and quantitative mass spectrometry. This high-purity compound is essential for pharmaceutical R&D laboratories, analytical chemistry facilities, and academic institutions engaged in isotope dilution methods, pharmacokinetics, and proteomics research.

Application

• Internal Standard for LC-MS/MS: Used as a deuterated internal standard in liquid chromatography-tandem mass spectrometry for the precise quantification of related amine or nitroso compounds in complex biological matrices.
• Metabolic Tracing Studies: Employed in pharmaceutical research to trace the metabolic fate and biotransformation pathways of drug candidates and their metabolites.
• Mechanistic Reaction Studies: Acts as a probe in chemical reaction mechanism elucidation, leveraging the kinetic isotope effect (KIE) of deuterium.
• Proteomics and Biomarker Research: Facilitates relative and absolute quantification in proteomic workflows and biomarker validation assays.
• Synthesis of Labeled Compounds: Serves as a key building block for the synthesis of more complex deuterium-labeled molecules for use as reference standards.
• Quality Control Reference Material: Used in the development and validation of analytical methods within quality control laboratories for the pharmaceutical and chemical industries.

Basic Information

Item	Details
Product Name	p-(Dimethyl-D6-Amino)Nitrosobenzene
CAS No.	1398065-85-4
Molecular Formula	C8D6N2O
Molecular Weight	152.19 g/mol
Synonyms	4-(Dimethylamino-d6)nitrosobenzene; N,N-Dimethyl-d6-4-nitrosoaniline; p-Nitroso-N,N-dimethylaniline-d6; Deuteron-p-Nitroso-N,N-dimethylaniline; 4-Nitroso-N,N-bis(trideuteriomethyl)benzenamine; Deuterated p-Nitroso Dimethylaniline; (Dimethyl-d6-amino)(4-nitrosophenyl)amine
EINECS	Contact for details

Quality Control

Every batch of p-(Dimethyl-D6-Amino)Nitrosobenzene is produced and tested under a strict quality management system. We guarantee high chemical and isotopic purity, with comprehensive characterization using NMR (¹H, ¹³C), mass spectrometry, and HPLC. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic enrichment (D-atom %), and all relevant analytical data to ensure compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Dark green to black crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.