Description

3-(3,4-Dimethoxy-D6-Phenyl)Propanoic-D4 Acid is a high-purity, deuterium-labeled derivative of 3,4-dimethoxyphenylpropanoic acid, a key intermediate in organic synthesis. This compound is specifically designed for use as an internal standard in quantitative mass spectrometry, providing unmatched accuracy and reliability in analytical workflows. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and advanced material sectors who require precise isotopic labeling for method development and validation.

Application

• Internal Standard for LC-MS/MS: Primary application as a stable isotope-labeled internal standard for the accurate quantification of 3,4-dimethoxyphenylpropanoic acid and related metabolites in complex biological matrices.
• Pharmaceutical Research: Critical for pharmacokinetic (PK), pharmacodynamic (PD), and drug metabolism studies, ensuring data integrity in regulatory submissions.
• Metabolomics and Biomarker Discovery: Enables precise relative and absolute quantification in profiling studies for disease research and diagnostic development.
• Agrochemical Analysis: Used in the trace analysis of pesticides, herbicides, and their environmental degradation products.
• Chemical Synthesis Tracer: Acts as a deuterated building block or tracer in mechanistic studies and the synthesis of novel labeled compounds.
• Forensic and Doping Control: Supports high-confidence analytical methods in forensic toxicology and anti-doping programs.

Basic Information

Product Name	3-(3,4-Dimethoxy-D6-Phenyl)Propanoic-D4 Acid
CAS No.	1398065-72-9
Molecular Formula	C11D10H2O4
Molecular Weight	~216.27 g/mol
Synonyms	3,4-Dimethoxy-D6-phenylpropanoic-D4 acid; 3-(3,4-Dimethoxyphenyl-D6)propionic-3,3,4,4-D4 acid; Deuterated 3,4-Dimethoxyphenylpropanoic Acid; 3,4-Dimethoxyphenylpropanoic Acid-d10; 3,4-Dimethoxy-D6-hydrocinnamic-D4 Acid; (3,4-Dimethoxyphenyl)propanoic Acid-d10; D10-3,4-Dimethoxyphenylpropanoic Acid; 1398065-72-9
EINECS	Contact for details

Quality Control

Every batch of 3-(3,4-Dimethoxy-D6-Phenyl)Propanoic-D4 Acid is manufactured under strict quality management systems. We guarantee high chemical and isotopic purity through comprehensive analytical techniques including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (typically ≥98% by HPLC), isotopic enrichment (typically ≥98 atom % D), and other critical specifications to ensure it meets the rigorous demands of analytical reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This material is light-sensitive (store away from light). For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.