Description

2-(3-Ethoxy-4-Methoxy-D3-Phenyl)Ethyl-1,1,2,2-D4-Amine Hcl is a high-purity, deuterium-labeled compound essential for advanced analytical and research applications. This material serves as a critical internal standard or reference material in quantitative mass spectrometry, enabling precise measurement and method validation. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers engaged in drug metabolism and pharmacokinetics (DMPK) studies, bioanalytical method development, and forensic analysis.

Application

• Internal Standard for LC-MS/MS: Used as a stable isotope-labeled internal standard in liquid chromatography-tandem mass spectrometry for the accurate quantification of its non-deuterated counterpart or related analytes in complex biological matrices.
• Drug Metabolism Studies (DMPK): Critical in pharmaceutical research for tracing metabolic pathways, studying pharmacokinetics, and identifying metabolites to support drug discovery and development.
• Bioanalytical Method Development & Validation: Employed to enhance the specificity, accuracy, and precision of analytical methods for compliance with FDA, EMA, and ICH guidelines.
• Forensic and Clinical Toxicology: Supports the detection and quantification of specific amine-based compounds or their metabolites in forensic analysis and clinical diagnostic assays.
• Isotope Dilution Mass Spectrometry (IDMS): Applied in high-accuracy measurement techniques where the deuterated compound is used to correct for analyte loss during sample preparation and instrument variability.
• Chemical Reference Standard: Serves as a certified reference material (CRM) for calibrating instruments and ensuring the reliability of analytical data in quality control laboratories.

Basic Information

Product Name	2-(3-Ethoxy-4-Methoxy-D3-Phenyl)Ethyl-1,1,2,2-D4-Amine Hcl
CAS No.	1398065-60-5
Molecular Formula	C11H11D7ClNO2 *
Molecular Weight	Contact for details
Synonyms	2-(3-Ethoxy-4-methoxy-D3-phenyl)ethyl-1,1,2,2-D4-amine hydrochloride
2-[3-Ethoxy-4-(methoxy-d3)phenyl]ethan-1,1,2,2-d4-amine hydrochloride
Deuterated 2-(3-Ethoxy-4-Methoxyphenyl)ethylamine Hydrochloride
2-(3-Ethoxy-4-Methoxy-D3-Phenyl)Ethane-D4-Amine Hcl
1398065-60-5
Deuterium Labeled Amine Hcl Standard
D7-2-(3-Ethoxy-4-Methoxyphenyl)ethylamine Hydrochloride
EINECS	Contact for details

* Formula accounts for deuterium (D) substitution at specified positions.

Quality Control

Every batch of 2-(3-Ethoxy-4-Methoxy-D3-Phenyl)Ethyl-1,1,2,2-D4-Amine Hcl is manufactured and analyzed under strict quality systems. We guarantee high chemical purity and isotopic enrichment, verified by advanced spectroscopic and chromatographic techniques including NMR, HPLC, and MS. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific purity, isotopic purity (D-enrichment), and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.