Description

N,N,N,n-Tetramethyl-1,3-Propanediamine-D18 is a deuterated analog of the versatile diamine ligand and catalyst precursor, N,N,N',N'-Tetramethyl-1,3-propanediamine (TMPDA). This compound is specifically designed for advanced research and development applications where isotopic labeling is critical. It serves as a valuable tool in mechanistic studies, spectroscopy, and pharmaceutical research, particularly in the investigation of reaction pathways and metabolic processes. Key industries that utilize this specialty chemical include pharmaceutical R&D, academic research, and advanced materials science.

Application

• NMR Spectroscopy & Mechanistic Studies: Acts as a deuterated internal standard or probe in Nuclear Magnetic Resonance (NMR) spectroscopy to elucidate molecular structures and reaction mechanisms without signal interference from protons.
• Pharmaceutical Research: Used in the synthesis of deuterated drug candidates for pharmacokinetic (PK) and pharmacodynamic (PD) studies, improving metabolic stability and tracing drug distribution.
• Catalysis Research: Serves as a deuterated ligand or precursor in organometallic chemistry and homogeneous catalysis research, allowing for detailed kinetic and mechanistic analysis.
• Polymer Science: Employed in the development of specialized polymers and coatings where deuterated monomers are required for neutron scattering studies to analyze polymer dynamics and morphology.
• Analytical Chemistry: Functions as a high-purity reference standard in Mass Spectrometry (MS) and other analytical techniques for method development and calibration.
• Isotope Labeling Synthesis: A key building block for the preparation of more complex deuterated organic compounds and fine chemicals used across various research disciplines.

Basic Information

Item	Detail
Product Name	N,N,N,n-Tetramethyl-1,3-Propanediamine-D18
CAS No.	1398065-52-5
Molecular Formula	C7D18N2
Molecular Weight	~162.33 g/mol (Deuterated form)
Synonyms	1,3-Propanediamine, N,N,N',N'-tetramethyl-, d18; TMPDA-d18; Perdeuterated TMPDA; N,N,N',N'-Tetramethyl-1,3-propanediamine-d18; 3-(Dimethylamino)-N,N-dimethyl-1-propanamine-d18; TMDPA-d18; Deuteron TMPDA; Tetramethylpropanediamine-d18
EINECS	Contact for details

Quality Control

Our N,N,N,n-Tetramethyl-1,3-Propanediamine-D18 is produced under strict quality management protocols to ensure the highest isotopic and chemical purity for research applications. Each batch is characterized using advanced analytical techniques including NMR, GC-MS, and HPLC to verify deuterium incorporation and chemical identity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain purity and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (GC)	≥ 97%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.