Description

n-Hexadecyl-1,1,2,2-D4 Alcohol is a deuterium-labeled analog of cetyl alcohol, a long-chain fatty alcohol. This stable isotope-labeled compound is essential for advanced analytical research, providing a critical internal standard for precise quantification and metabolic pathway tracing. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors who require high-fidelity tools for mass spectrometry, NMR spectroscopy, and pharmacokinetic studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis of lipids, surfactants, and related compounds to ensure accuracy and reproducibility.
• Metabolic Pathway Tracing: Employed in deuterium labeling studies to investigate the metabolism, absorption, and distribution of fatty alcohols and their derivatives in biological systems.
• NMR Spectroscopy Solvent & Reagent: Serves as a deuterated reagent or a probe in nuclear magnetic resonance studies to elucidate molecular structure and dynamics without signal interference.
• Pharmaceutical Research & Development: Critical in the development and validation of analytical methods for drug substances and excipients containing alkyl chains.
• Biochemical Research: Used in studies of lipid bilayers, membrane fluidity, and surfactant behavior where isotopic labeling is required.
• Chemical Synthesis Intermediate: Acts as a labeled building block for the synthesis of more complex deuterated compounds, such as surfactants, plasticizers, or pharmaceutical intermediates.

Basic Information

Item	Details
Product Name	n-Hexadecyl-1,1,2,2-D4 Alcohol
CAS No.	1398065-49-0
Molecular Formula	C₁₆H₃₂D₄O
Molecular Weight	244.46 g/mol (approx.)
Synonyms	1-Hexadecanol-1,1,2,2-d4; Cetyl Alcohol-d4; Palmityl Alcohol-d4; n-Cetyl Alcohol-d4; Hexadecan-1-ol-1,1,2,2-d4; Deuterated Cetyl Alcohol; [1,1,2,2-D4]Hexadecan-1-ol; 1-Hexadecyl Alcohol-d4
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced and controlled under a strict quality management system. Each batch of n-Hexadecyl-1,1,2,2-D4 Alcohol is characterized by NMR, MS, and HPLC to confirm chemical identity, isotopic purity (typically >98 atom % D), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all analytical results is provided with every shipment to ensure full traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Chemical Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.