Description

6-Bromo-4,4-Dimethyl-3,4-Dihydroisoquinolin-1(2H)-One is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. Its value lies in its unique brominated dihydroisoquinolinone scaffold, which is crucial for synthesizing complex molecules in medicinal chemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Building Block: Used in various organic transformations, including cross-coupling reactions, due to the reactivity of the bromine substituent.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Material Science: Can be utilized in the synthesis of specialized organic materials and ligands for catalysis.

Basic Information

Product Name	6-Bromo-4,4-Dimethyl-3,4-Dihydroisoquinolin-1(2H)-One
CAS No.	1396777-58-4
Molecular Formula	C11H12BrNO
Molecular Weight	254.12 g/mol
Synonyms	6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroisoquinolin-1-one; 6-Bromo-4,4-dimethyl-3,4-dihydro-1H-isoquinolin-1-one; 1(2H)-Isoquinolinone, 6-bromo-3,4-dihydro-4,4-dimethyl-; 6-Bromo-4,4-dimethyl-1-oxo-1,2,3,4-tetrahydroisoquinoline; 1396777-58-4
EINECS	Contact for details

Quality Control

Our 6-Bromo-4,4-Dimethyl-3,4-Dihydroisoquinolin-1(2H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.