Description

1-Bromo-3-Chloro-4-Methylisoquinoline is a high-purity, multi-halogenated isoquinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecular architectures, particularly in pharmaceutical discovery and materials science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise building blocks for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the halogenated isoquinoline core.
• Material Science Precursor: Serves as a monomer or functional unit in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions to introduce complex functionalities.
• Ligand and Catalyst Development: Utilized for constructing novel chelating ligands in coordination chemistry and catalysis.
• Academic & R&D: A valuable reagent for methodological studies and exploring new reaction pathways in organic chemistry laboratories.

Basic Information

Product Name	1-Bromo-3-Chloro-4-Methylisoquinoline
CAS No.	1396762-45-0
Molecular Formula	C10H7BrClN
Molecular Weight	256.53 g/mol
Synonyms	1-Bromo-3-chloro-4-methylisoquinoline; 4-Methyl-1-bromo-3-chloro-isoquinoline; Isoquinoline, 1-bromo-3-chloro-4-methyl-; 3-Chloro-1-bromo-4-methylisoquinoline
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Chloro-4-Methylisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.