Description

Ethyl 3-Amino-7-(Trifluoromethyl)-1-Benzothiophene-2-Carboxylate is a high-value, multifunctional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its unique molecular architecture, combining an electron-rich amino group with a robust benzothiophene core and a lipophilic trifluoromethyl substituent, enabling precise molecular design. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets, leveraging the benzothiophene scaffold's bioactivity.
• Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances metabolic stability and bioavailability.
• Material Science Building Block: Used in the development of organic semiconductors, liquid crystals, and advanced polymers due to its conjugated system and tunable electronic properties.
• Dye and Pigment Synthesis: Functions as an intermediate for creating specialized heterocyclic dyes and fluorescent markers.
• Custom Synthesis & Contract Research: An essential starting material for custom synthesis projects and discovery chemistry in contract research organizations (CROs).

Basic Information

Item	Details
Product Name	Ethyl 3-Amino-7-(Trifluoromethyl)-1-Benzothiophene-2-Carboxylate
CAS No.	1396503-80-2
Molecular Formula	C₁₂H₁₀F₃NO₂S
Molecular Weight	289.27 g/mol
Synonyms	3-Amino-2-(ethoxycarbonyl)-7-(trifluoromethyl)-1-benzothiophene; Ethyl 3-amino-7-(trifluoromethyl)benzo[b]thiophene-2-carboxylate; 7-(Trifluoromethyl)-1-benzothiophene-2-carboxylic acid, 3-amino-, ethyl ester; 3-Amino-7-(trifluoromethyl)-1-benzothiophene-2-carboxylic acid ethyl ester; 1396503-80-2; ATB-EFC; Amino-trifluoromethyl-benzothiophene carboxylate ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-Amino-7-(Trifluoromethyl)-1-Benzothiophene-2-Carboxylate is produced and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and development applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.