Description

Methyl n-(1,2,3,4-Tetrahydroisoquinolin-5-Yl)Carbamate Hydrochloride is a high-purity organic salt of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for research and development. It is primarily utilized by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in the discovery and development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting neurological and other therapeutic areas.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Employed in the construction of complex heterocyclic compounds and specialized fine chemicals.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biochemical Research: Potential use as a tool compound for probing biological pathways and enzyme interactions in life science research.

Basic Information

Product Name	Methyl n-(1,2,3,4-Tetrahydroisoquinolin-5-Yl)Carbamate Hydrochloride
CAS No.	1394041-21-4
Molecular Formula	C12H16N2O2·HCl
Molecular Weight	256.73 g/mol
Synonyms	Methyl (1,2,3,4-Tetrahydroisoquinolin-5-yl)carbamate Hydrochloride; 5-[(Methoxycarbonyl)amino]-1,2,3,4-tetrahydroisoquinoline Hydrochloride; 5-Amino-1,2,3,4-tetrahydroisoquinoline Methylcarbamate Hydrochloride; Methyl 5-Amino-3,4-dihydro-1H-isoquinoline-2-carboxylate Hydrochloride; TIQ-5-Carbamate HCl; CAS 1394041-21-4
EINECS	Contact for details

Quality Control

Our Methyl n-(1,2,3,4-Tetrahydroisoquinolin-5-Yl)Carbamate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.