Description

7-Chloro-4,4-Difluoroisoquinoline-1,3(2H,4H)-Dione (Wxc00573) is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated isoquinoline-dione structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted properties. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated fluorinated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where the difluoro and chloro substituents can enhance biological activity and environmental stability.
• Material Science: Acts as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials due to its rigid, heteroaromatic structure.
• Chemical Biology Probe: Utilized in academic and industrial research to create molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Fluorine Chemistry Building Block: Provides a valuable template for further synthetic elaboration, leveraging the reactivity of the chloro and difluoro groups for cross-coupling and substitution reactions.

Basic Information

Product Name	7-Chloro-4,4-Difluoroisoquinoline-1,3(2H,4H)-Dione (Wxc00573)
CAS No.	1393726-80-1
Molecular Formula	C9H4ClF2NO2
Molecular Weight	231.59 g/mol
Synonyms	7-Chloro-4,4-difluoro-1H,3H-isoquinoline-1,3-dione; 7-Chloro-4,4-difluoro-2,4-dihydro-1H-isoquinoline-1,3-dione; 7-Chloro-4,4-difluoroisoquinoline-1,3(2H,4H)-dione; WXC-00573; Wxc00573; 1393726-80-1; 4,4-Difluoro-7-chloroisoquinoline-1,3(2H,4H)-dione
EINECS	Contact for details

Quality Control

Our 7-Chloro-4,4-Difluoroisoquinoline-1,3(2H,4H)-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.