Description

3,3-Dimethyl-6-(trifluoromethyl)-2-indolinone is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a substituted indolinone scaffold with a trifluoromethyl group, makes it a critical intermediate for developing novel bioactive molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-cancer drug discovery programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for functional organic materials, including organic light-emitting diodes (OLEDs) and specialty polymers.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized fluorinated heterocycles.

Basic Information

Product Name	3,3-Dimethyl-6-(trifluoromethyl)-2-indolinone
CAS No.	1393491-69-4
Molecular Formula	C11H10F3NO
Molecular Weight	229.20 g/mol
Synonyms	6-(Trifluoromethyl)-3,3-dimethylindolin-2-one; 3,3-Dimethyl-6-(trifluoromethyl)indolin-2-one; 2-Indolinone, 3,3-dimethyl-6-(trifluoromethyl)-; 3,3-Dimethyl-6-trifluoromethyl-2-indolinone; 6-Trifluoromethyl-3,3-dimethyl-2-indolinone
EINECS	Contact for details

Quality Control

Our 3,3-Dimethyl-6-(trifluoromethyl)-2-indolinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.