Description

n-(5-Aminosulfonylthiophen-2-Yl)Succinimide is a high-purity, specialized heterocyclic building block featuring both a succinimide and an aminosulfonyl-substituted thiophene moiety. This compound is of significant value in pharmaceutical research and development, serving as a key intermediate for the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules. It is primarily sought after by research institutions, custom synthesis houses, and pharmaceutical companies engaged in medicinal chemistry, particularly for projects targeting enzyme inhibition and the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its reactive functional groups.
• Custom Synthesis: Serves as a starting material or intermediate for contract research organizations (CROs) and CDMOs producing bespoke compounds.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or affinity labels for biological target identification and validation.
• Agrochemical Research: May be utilized in the discovery and development of new crop protection agents and pesticides.
• Material Science: Can be investigated as a monomer or precursor for specialty polymers with unique electronic or thermal properties.

Basic Information

Product Name	n-(5-Aminosulfonylthiophen-2-Yl)Succinimide
CAS No.	1393441-98-9
Molecular Formula	C8H8N2O4S2
Molecular Weight	260.29 g/mol
Synonyms	2-(5-Sulfamoylthiophen-2-yl)-1H-pyrrole-1,5(2H)-dione; 1-(5-Sulfamoylthiophen-2-yl)pyrrolidine-2,5-dione; 5-(2,5-Dioxopyrrolidin-1-yl)thiophene-2-sulfonamide; N-(5-Sulfamoylthiophen-2-yl)succinimide; Succinimide, N-(5-sulfamoyl-2-thienyl)-
EINECS	Contact for details

Quality Control

Our n-(5-Aminosulfonylthiophen-2-Yl)Succinimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.