Description

4-(1-(2-Chloro-6-(Trifluoromethyl)Benzoyl)-1H-Indazol-3-Yl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially for small molecule therapeutics.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• API Development: Employed in the development and scale-up processes for new active pharmaceutical ingredients, leveraging its indazole-benzoic acid core.
• Chemical Biology Probes: Can be utilized to create specialized molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for the contract synthesis of more complex, proprietary molecules for client-specific R&D projects.

Basic Information

Product Name	4-(1-(2-Chloro-6-(Trifluoromethyl)Benzoyl)-1H-Indazol-3-Yl)Benzoic Acid
CAS No.	1392809-08-3
Molecular Formula	C22H12ClF3N2O3
Molecular Weight	444.79 g/mol
Synonyms	4-[1-[(2-Chloro-6-(trifluoromethyl)phenyl)carbonyl]indazol-3-yl]benzoic acid; 4-(1-(2-Chloro-6-(trifluoromethyl)benzoyl)-1H-indazol-3-yl)benzoic acid; Benzoic acid, 4-[1-[[2-chloro-6-(trifluoromethyl)phenyl]carbonyl]-1H-indazol-3-yl]-; 1392809-08-3; 4-(1-(2-Chloro-6-trifluoromethyl-benzoyl)-1H-indazol-3-yl)-benzoic acid
EINECS	Contact for details

Quality Control

Our production of 4-(1-(2-Chloro-6-(Trifluoromethyl)Benzoyl)-1H-Indazol-3-Yl)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.