Description

6-Bromo-3,3-Dimethyl-2,3-Dihydro-1H-Indole-4-Carboxylic Acid is a high-purity, functionalized indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery programs and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used as a building block for developing new pesticides and herbicides with enhanced efficacy and selectivity.
• Chemical Biology Probe Development: Employed in the creation of molecular probes for studying enzyme function and biological pathways due to its modifiable indole core.
• Material Science: Serves as a monomer or functional additive in the synthesis of advanced polymers and organic electronic materials.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental research in heterocyclic chemistry and method development.
• Custom Synthesis: The foundation for bespoke chemical synthesis services, enabling the production of tailored derivatives for specific client projects.

Basic Information

Product Name	6-Bromo-3,3-Dimethyl-2,3-Dihydro-1H-Indole-4-Carboxylic Acid
CAS No.	1392803-44-9
Molecular Formula	C11H12BrNO2
Molecular Weight	270.12 g/mol
Synonyms	6-Bromo-3,3-dimethylindoline-4-carboxylic acid; 4-Carboxy-6-bromo-3,3-dimethylindoline; 1H-Indole-4-carboxylic acid, 6-bromo-2,3-dihydro-3,3-dimethyl-; 6-Bromo-3,3-dimethyl-1,2,3,4-tetrahydro-4-carboxyindole; 1392803-44-9; 6-Br-3,3-diMe-indoline-4-COOH
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-3,3-Dimethyl-2,3-Dihydro-1H-Indole-4-Carboxylic Acid is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and MS to meet the exacting requirements of research and development. Certificates of Analysis (COA) with full batch traceability are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.