Description

n-Boc-Peg4-Bromide CAS NO 1392499-32-9 is a high-purity, functionalized polyethylene glycol (PEG) derivative featuring a tert-butyloxycarbonyl (Boc) protecting group and a terminal bromide. This compound is a critical building block in the synthesis of complex molecules, enabling precise control over conjugation, solubility, and molecular architecture. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors for developing novel therapeutics, drug delivery systems, and functional polymers.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of antibody-drug conjugates (ADCs) and other targeted biopharmaceuticals.
• Bioconjugation Linker: Used to attach drugs, dyes, or other functional molecules to peptides, proteins, or nanoparticles via its reactive bromide group.
• Polymer Chemistry: Serves as a functional initiator or monomer in the controlled polymerization of PEG-based materials for hydrogels and smart polymers.
• Prodrug Synthesis: Facilitates the creation of prodrugs with improved pharmacokinetic properties through its cleavable Boc group and PEG spacer.
• Chemical Biology Probes: Employed in the development of molecular probes and diagnostic agents for research applications.
• Material Science: Used to modify surface properties and introduce functional handles onto various substrates and nanomaterials.

Basic Information

Product Name	n-Boc-Peg4-Bromide
CAS No.	1392499-32-9
Molecular Formula	C17H33BrNO7
Molecular Weight	443.35 g/mol
Synonyms	1-Boc-amino-3,6,9,12-tetraoxapentadec-14-yl bromide; 2-[2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]ethoxy]ethyl N-(tert-butoxycarbonyl)carbamate; Boc-NH-PEG4-Br; tert-Butyl N-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate; 14-Bromo-3,6,9,12-tetraoxa-15-azapentadecan-1-oic acid tert-butyl ester; Boc-PEG4-Br; N-Boc-15-amino-4,7,10,13-tetraoxapentadecyl bromide
EINECS	Contact for details

Quality Control

Our n-Boc-Peg4-Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your research and cGMP-compliant workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.