Description

Sulfadimethoxypyrimidine D4 is a deuterated analog of the sulfonamide antibiotic sulfadimethoxine, specifically labeled with four deuterium atoms. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical results. It is a critical material for researchers and quality control laboratories in the pharmaceutical, veterinary medicine, and food safety sectors who require precise measurement of sulfadimethoxine and its metabolites.

Application

• Internal standard for the quantitative LC-MS/MS analysis of sulfadimethoxine in biological matrices (e.g., plasma, tissue, milk).
• Metabolite studies and pharmacokinetic research in veterinary and human pharmaceutical development.
• Quality control and method validation in pharmaceutical manufacturing of sulfonamide drugs.
• Residue testing and monitoring programs in food safety, particularly for animal-derived products.
• Environmental analysis for tracking veterinary antibiotic contamination in water and soil samples.
• Use in certified reference material (CRM) production for analytical laboratories.

Basic Information

Product Name	Sulfadimethoxypyrimidine D4
CAS No.	1392211-88-9
Molecular Formula	C12H10D4N4O4S
Molecular Weight	314.35 g/mol
Synonyms	2,4-Dimethoxy-6-sulfanilamidopyrimidine-d4; Sulfadimethoxine-d4; N1-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide-d4; 4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide-d4; Sulfadimethoxypyrimidine-d4; Deuterated Sulfadimethoxine; [2H4]-Sulfadimethoxine; SDM-d4
EINECS	Contact for details

Quality Control

Our Sulfadimethoxypyrimidine D4 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and MS, to confirm identity, purity, and deuterium incorporation. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the product at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Incorporation)	≥ 98.0 atom % D
Chemical Purity (by HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.