Description

Sodium 4-Phenylbutyrate-D11 is a high-purity, deuterium-labeled derivative of the pharmaceutical agent sodium phenylbutyrate. This stable isotope-labeled compound is essential for advanced analytical research, providing a critical internal standard for precise quantification and metabolic pathway tracing. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors.

Application

• Internal Standard for Quantitative Analysis: Used in LC-MS, GC-MS, and HPLC methods for the accurate measurement of sodium phenylbutyrate and its metabolites in biological matrices.
• Pharmacokinetic and Metabolic Studies: Enables detailed investigation of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Biochemical Research: Serves as a tracer in studies of fatty acid metabolism and the role of phenylbutyrate in modulating cellular pathways.
• Pharmaceutical Quality Control: Critical for developing and validating robust assay methods to ensure the purity and potency of active pharmaceutical ingredients (APIs) and finished drug products.
• Stable Isotope Labeling: Acts as a starting material or reference compound in the synthesis of other deuterated molecules for research purposes.

Basic Information

Product Name	Sodium 4-Phenylbutyrate-D11
CAS No.	1392208-11-5
Molecular Formula	C10D11NaO2
Molecular Weight	203.24 g/mol (approx.)
Synonyms	Sodium Phenylbutyrate-D11; 4-Phenylbutyric Acid-D11 Sodium Salt; Sodium 4-Phenyl[2,2,3,3,4,4,5,5,6,6,6-D11]butyrate; Ammonaps-D11 (deuterated analog); Buphenyl-D11 (deuterated analog); (4-Phenylbutyryl-D11) Sodium Salt; NSC 113455-D11
EINECS	Contact for details

Quality Control

Our Sodium 4-Phenylbutyrate-D11 is manufactured under strict quality management systems. Each batch is characterized and tested to ensure high chemical and isotopic purity, meeting the stringent requirements for research and analytical applications. Comprehensive testing includes assay, isotopic enrichment (D-enrichment), and identification by spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.