Description

(1S,3S)-1,3-Diallyl-1,2,3,4-Tetrahydroisoquinoline CAS NO 1391440-71-3 is a chiral, substituted tetrahydroisoquinoline derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated building block and key intermediate for the development of complex molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets and alkaloid-based therapeutics.
• Asymmetric Catalysis Ligand Synthesis: Used to construct complex ligand frameworks for transition metal catalysts employed in enantioselective transformations.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in structure-activity relationship (SAR) studies.
• Natural Product Synthesis: A key intermediate in the total synthesis of complex natural products containing the tetrahydroisoquinoline core.
• Agrochemical Development: Employed in the research and development of novel, biologically active compounds for crop protection.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	(1S,3S)-1,3-Diallyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	1391440-71-3
Molecular Formula	C₁₇H₂₁N
Molecular Weight	239.36 g/mol
Synonyms	(1S,3S)-1,3-Diallyl-1,2,3,4-tetrahydroisoquinoline; (1S,3S)-1,3-Diallyl-1,2,3,4-THIQ; 1,2,3,4-Tetrahydroisoquinoline, 1,3-diallyl-, (1S,3S)-; (1S,3S)-1,3-Di(prop-2-en-1-yl)-1,2,3,4-tetrahydroisoquinoline; (S,S)-1,3-Diallyl-1,2,3,4-tetrahydroisoquinoline; Chiral Diallyl Tetrahydroisoquinoline; 1,3-Diallyl-THIQ (chiral)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) are available upon request, detailing specifications such as chiral purity (HPLC), chemical purity (HPLC/GC), and residual solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.