Description

Vigabatrin (Hydrochloride) CAS NO 1391054-02-6 is a high-purity pharmaceutical intermediate and active ingredient, specifically the hydrochloride salt of the antiepileptic drug vigabatrin. This compound is critical for ensuring the efficacy and safety of finished pharmaceutical products targeting refractory complex partial seizures and infantile spasms. It is primarily required by pharmaceutical manufacturers and advanced research institutions engaged in the development and production of neurological therapeutics.

Application

• Active Pharmaceutical Ingredient (API) for the manufacture of antiepileptic medications.
• Neurological Research as a reference standard in studies of GABA transaminase inhibition.
• Pharmaceutical Intermediates in the synthesis of complex drug formulations.
• Analytical Standard for quality control and method validation in pharmaceutical laboratories.
• Clinical Trial Material for investigational new drug (IND) applications and studies.
• Generic Drug Production for cost-effective therapeutic alternatives.

Basic Information

Product Name	Vigabatrin (Hydrochloride)
CAS No.	1391054-02-6
Molecular Formula	C6H12NO2Cl
Molecular Weight	165.62 g/mol
Synonyms	Vigabatrin HCl; Vigabatrin hydrochloride; (RS)-4-Aminohex-5-enoic acid hydrochloride; GVG hydrochloride; γ-Vinyl-GABA hydrochloride; Sabril impurity standard (hydrochloride form); (±)-Vigabatrin hydrochloride
EINECS	Contact for details

Quality Control

Our Vigabatrin (Hydrochloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and compliance with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Chiral Purity	≥ 99.0% (by chiral HPLC)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.