Description

n-Boc-1-Bromo-2-Methyl-2-Propanamine is a protected amine building block of significant value in synthetic organic chemistry. Its core value lies in providing a reactive bromoalkyl handle adjacent to a tert-butyloxycarbonyl (Boc)-protected primary amine, enabling selective and sequential functionalization. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in constructing amine-containing pharmacophores and side chains.
• Peptidomimetics Synthesis: Used to introduce protected aminoalkyl functionalities into peptide analogs and mimetics to enhance stability and bioavailability.
• Agrochemical Research: Serves as a versatile intermediate in the development of new herbicides, fungicides, and insecticides requiring specific amine-alkyl architectures.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts.
• Polymer Chemistry: Can be utilized as a functional monomer or chain-transfer agent in the synthesis of specialty polymers with amine functionality.
• Chemical Biology Probes: Acts as a precursor for labeling reagents and molecular probes used in biochemical and cellular studies.

Basic Information

Product Name	n-Boc-1-Bromo-2-Methyl-2-Propanamine
CAS No.	1391026-60-0
Molecular Formula	C9H18BrNO2
Molecular Weight	252.15 g/mol
Synonyms	1-Bromo-2-methyl-2-((tert-butoxycarbonyl)amino)propane; tert-Butyl (1-bromo-2-methylpropan-2-yl)carbamate; (1-Bromo-2-methyl-2-propyl)carbamic Acid tert-Butyl Ester; N-Boc-2-amino-2-methylpropyl Bromide; N-(tert-Butoxycarbonyl)-1-bromo-2-methyl-2-propanamine; Boc-AMB; Boc-2-amino-2-methylpropyl bromide
EINECS	Contact for details

Quality Control

Our n-Boc-1-Bromo-2-Methyl-2-Propanamine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and scale-up applications. Each batch is analyzed using advanced techniques including HPLC, NMR, and GC to verify identity and purity. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.