Description

(6-Chloro-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methanol is a high-purity, synthetically valuable heterocyclic building block. This compound is essential for pharmaceutical research and development, serving as a key chiral intermediate in the synthesis of complex bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of potential central nervous system (CNS) active compounds and other therapeutic agents.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its tetrahydroisoquinoline scaffold.
• Organic Synthesis Building Block: Employed in asymmetric synthesis and medicinal chemistry for constructing complex nitrogen-containing heterocycles.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Ligand and Catalyst Precursor: Utilized in the development of novel chiral ligands for catalytic asymmetric transformations.

Basic Information

Product Name	(6-Chloro-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methanol
CAS No.	1391017-09-6
Molecular Formula	C10H12ClNO
Molecular Weight	197.66 g/mol
Synonyms	6-Chloro-1,2,3,4-tetrahydro-1-isoquinolinemethanol; (6-Chloro-1,2,3,4-tetrahydroisoquinolin-1-yl)methanol; 1-(Hydroxymethyl)-6-chloro-1,2,3,4-tetrahydroisoquinoline; 6-Chloro-1-(hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline; 6-Chloro-THIQ-1-yl-methanol
EINECS	Contact for details

Quality Control

Our (6-Chloro-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.