Description

5-Bromo-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid is a high-purity, functionalized tetrahydroisoquinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex, biologically active molecules, enabling precise structural modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential therapeutic agents, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the bioactive tetrahydroisoquinoline scaffold.
• Chemical Biology: Employed as a probe or linker in the design of molecular tools for studying biological pathways and protein interactions.
• Medicinal Chemistry: Serves as a core structure for structure-activity relationship (SAR) studies and lead optimization programs.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	5-Bromo-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid
CAS No.	1391006-26-0
Molecular Formula	C10H10BrNO2
Molecular Weight	256.10 g/mol
Synonyms	5-Bromo-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic acid; 1-Carboxy-5-bromo-1,2,3,4-tetrahydroisoquinoline; 5-Bromo-THIQ-1-carboxylic acid; 5-Bromo-1,2,3,4-tetrahydroisoquinoline-1-carboxylate; 5-Bromo-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid; 5-Bromotetrahydroisoquinoline-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all relevant specifications. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.