Description

n-Methyl-n-[3-[[[(8β)-6-(2-Propen-1-Yl)Ergolin-8-Yl]Carbonyl]Amino]Propyl]Carbamic Acid 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate belonging to the ergoline alkaloid class. This compound is critical for research and development in the synthesis of novel therapeutic agents targeting neurological and cardiovascular systems. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex ergot alkaloid derivatives and potential active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new compounds for central nervous system (CNS) disorders.
• Preclinical Development: Serves as a critical precursor in the scale-up and process optimization for candidate drugs.
• Contract Synthesis: Supplied to CROs and CMOs for custom synthesis projects requiring high-fidelity ergoline scaffolds.
• Reference Standard: Can be utilized as a chromatographic or spectroscopic standard for analytical method development and quality control.

Basic Information

Item	Detail
Product Name	n-Methyl-n-[3-[[[(8β)-6-(2-Propen-1-Yl)Ergolin-8-Yl]Carbonyl]Amino]Propyl]Carbamic Acid 1,1-Dimethylethyl Ester
CAS No.	1390658-68-0
Molecular Formula	C28H38N4O3
Molecular Weight	478.63 g/mol
Synonyms	tert-Butyl N-methyl-N-[3-[[(8β)-6-(prop-2-en-1-yl)ergoline-8-carbonyl]amino]propyl]carbamate; BOC-Protected Ergoline Derivative; 6-Allyl-8β-[[[3-[(tert-Butoxycarbonyl)(methyl)amino]propyl]amino]carbonyl]ergoline; CAS 1390658-68-0; N-BOC-N'-Methyl-3-((6-allylergoline-8-carboxamido)propyl)urea; 6-Allylergoline-8-carboxylic acid [3-[(tert-butoxycarbonyl-methyl-amino)-propyl]-amide]
EINECS	Contact for details

Quality Control

Our n-Methyl-n-[3-[[[(8β)-6-(2-Propen-1-Yl)Ergolin-8-Yl]Carbonyl]Amino]Propyl]Carbamic Acid 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.