Description

Methyl 6-Bromo-3,3-Dimethyl-2,3-Dihydro-1H-Indole-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated indoline core structure. This compound is of significant value for its role as a versatile building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients in crop protection products.
• Organic Synthesis: Utilized in academic and industrial labs for constructing complex heterocyclic compounds due to its reactive bromine and ester functional groups.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Methyl 6-Bromo-3,3-Dimethyl-2,3-Dihydro-1H-Indole-4-Carboxylate
CAS No.	1389264-22-5
Molecular Formula	C₁₂H₁₄BrNO₂
Molecular Weight	284.15 g/mol
Synonyms	6-Bromo-3,3-dimethyl-1,2,3,4-tetrahydroindole-4-carboxylic acid methyl ester; Methyl 6-bromo-3,3-dimethyl-2,3-dihydro-1H-indole-4-carboxylate; 4-Carbomethoxy-6-bromo-3,3-dimethylindoline; 1389264-22-5; 6-Bromo-3,3-dimethylindoline-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Bromo-3,3-Dimethyl-2,3-Dihydro-1H-Indole-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.