Description

Ethyl 2-(4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-5-Yl)Acetate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs targeting various disease pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitor candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with targeted biological activity.
• Biochemical Reagent: Employed in biochemical assays and as a reference standard for analytical method development and validation in drug discovery pipelines.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client-sponsored drug discovery programs.

Basic Information

Product Name	Ethyl 2-(4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-5-Yl)Acetate
CAS No.	1388893-77-3
Molecular Formula	C15H15ClN2O2S
Molecular Weight	322.81 g/mol
Synonyms	Ethyl (4-chloro-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-5-yl)acetate; 5H-Cyclopenta[4,5]thieno[2,3-d]pyrimidine, 4-chloro-6,7-dihydro-, 5-acetic acid ethyl ester; 1388893-77-3; Ethyl 2-(4-chloro-5H,6H,7H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-5-yl)acetate; 4-Chloro-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-5-ylacetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Chloro-6,7-Dihydro-5H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-5-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure compliance with stringent in-house specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect against moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.